P82: Beneficial Effect of 5-HT Receptor Agonist Administration on Memory Rehabilitation after Closed Head Injury
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p82: beneficial effect of 5-ht receptor agonist administration on memory rehabilitation after closed head injury
the serotonin (5-ht) receptors are a group of g protein-coupled receptors (gpcrs) and ligand-gated ion channels that found in the central and peripheral nervous systems. 5ht receptor can substantially influence brain functions such as learning and memory, perception of the environment, mood states, and responses to alcohol and other drugs of abuse. lysergic acid diethylamide (lsd) as a 5ht rece...
full textImpairment of remote memory after closed head injury.
Evidence of partial retrograde amnesia for episodic memories of no personal salience was found in head injured patients (n = 10) tested during posttraumatic amnesia or shortly after its resolution (n = 10), but there was no selective preservation of the earliest memories. In contrast, head injured patients tested during posttraumatic amnesia exhibited relatively preserved retention of early aut...
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BACKGROUND 5-HT6 receptor (5-HT6R) has pluripotent roles regulating secretion of neurotransmitters. However, whether 5-HT6R is involved in the development of vascular dementia (VD) remains unclear. To evaluate the role and mechanism of 5-HT6R in VD, this study established a rat VD model to evaluate the effect of selective 5-HT6R agonist on the expression of 5-HT6R mRNA and neurotransmitter. MAT...
full textVentricular Changes after Closed Head Injury.
Introduction ALTHOUGH the majority of patients who sustain a closed head injury appear to make a complete and satisfactory recovery, some are left with residual disabilities, which interfere with their well-being and their adjustment to society. It is known that in such cases permanent structural changes often occur in the brain, but clinically it is difficult to ascertain their severity and ex...
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volume 2 issue 4
pages 132- 132
publication date 2014-12
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